Watsuki-sensei is best known for Rurouni Kenshin, all four OAVs, the movies, the manga, and the TV series. His other works include the Buso Renkin manga doing the story and artwork, and the Yahiko no Sakabato manga doing story and artwork in that as well. In Tokyo, Japan, on May 26, in the year 1970, a Watsuki-sensei was born. He was a child who practiced Kendo, but never progressed. o.o
Although, when in high school, he won the "Pop Step" award for his manga "Podmark." The inspiration for his passion for drawing manga came from his older brother, Osamu Tezuka (the godfather of anime and Atom Boy), and other artists as well. Nobuhiro Watsuki has collaborated with Takeshi Obata ( The mangaka for Hikaru No Go!). Just the same, he's had his share of having his own assistants, such as Eiichiro Oda (mangaka for One Piece) and Hiroyuki Takei (mangaka for Shaman King). And from what I've read, he assisted in the production of Arabian Lamp-Lamp and Chikara Mito Densetsu.
In 1992, Watsuki sent to Shueisha Publications his 31-page start-up chapter for the now super-famous Rurouni Kenshin. This peice was titled Rurouni: The Meiji Swordsman Romantic Story. This is the break that made him famous in Japan, and eventually, world famous.
If you would like to read more about Watsuki-sensei, you can go here.